PCI_E3 will be unavailable when installing M.2 SSD in M2_2 slot. However, if you want to use both of them simultaneously, you can set x1 for PCI_E3 and set x2 for M2_2 in BIOS.
ONBOARD GRAPHICS
1x HDMI 2.0b with HDR port, supports a maximum resolution of 4K 60Hz12
1x DisplayPort 1.4 port, supports a maximum resolution of 4K 60Hz12
Available only on processors featuring integrated graphics
Graphics specifications may vary depending on the CPU installed.